Antonio Jiménez Ruiz

Articles

• HENRÍQUEZ FIGUEREO, Andreina; ALCÓN CALDERÓN, María de las Mercedes; MORENO AMATRIA, Esther; SANMARTÍN GRIJALBA, Carmen; ESPUELAS MILLÁN, María Socorro; LUCIO ORTEGA, Héctor Elessar de; JIMÉNEZ RUIZ, Antonio; PLANO AMATRIAIN, Daniel; ."Next generation of selenocyanate and diselenides with upgraded leishmanicidal activity". (ISSN: 0045-2068). Bioorganic Chemistry. 2023 , vol 138 , num 106624 , p. 1 - 12 .  .

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• JIMÉNEZ RUIZ, Antonio; A. MESA-ARANGO, Jairo; M. OLAVE-VELANDIA, Ana; M. GARCÍA-MONTOYA, Gisela; P. ISAZA-AGUADO, Juan; F. ALZATE, Juan; ."Evaluation of new Toxocara canis chimeric antigens as an alternative to conventional TES-Ag for anti-Toxocara antibodies detection". Heliyon. 2022 , vol 8 , num 10

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• LUCIO ORTEGA, Héctor Elessar de; GARCÍA MARIN, Javier; SÁNCHEZ ALONSO, Patricia; GARCÍA SORIANO, Juan Carlos; TORO LONDOÑO, Miguel; VAQUERO LÓPEZ, Juan José; GAGO BADENAS, Federico; ALAJARÍN FERRÁNDEZ, Luis Ramón; JIMÉNEZ RUIZ, Antonio; ."Pyridazino-pyrrolo-quinoxalinium salts as highly potent and selective leishmanicidal agents targeting trypanothione reductase". (ISSN: 0223-5234). European Journal of Medicinal Chemistry. 2022 , vol 227 , num 113915 , p. 1 - 13 .  .

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• ETXEBESTE-MITXELTORENA , Mikel; PLANO , D; ESPUELAS , Socoro; MORENO MATEOS, David; AYDILLO , C.; JIMÉNEZ RUIZ, Antonio; GARCÍA-SORIANO , Juan Carlos; SANMARTÍN , Carmen; ."New phosphoramidates containing selenium as leishmanicidal agents". (ISSN: 0066-4804). Antimicrobial Agents and Chemotherapy. 2021 , p. AAC0059021 -

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• REVUELTO , Alejandro; DE LUCIO , Héctor; GARCÍA SORIANO, Juan Carlos; SÁNCHEZ-MURCIA , Pedro A.; GAGO BADENAS, Federico; JIMÉNEZ RUIZ, Antonio; CAMARASA RIUS, María José; VELÁZQUEZ , Sonsoles; ."Efficient Dimerization Disruption of Leishmania infantum Trypanothione Reductase by Triazole-phenyl-thiazoles". (ISSN: 0022-2623). Journal of Medicinal Chemistry. 2021 , vol 64 , num 9 , p. 6137 - 6160

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• ALCOLEA , Veronica; MORENO , Esther; ETXEBESTE-MITXELTORENA , Mikel; NAVARRO-BLASCO , Inigo; JIMÉNEZ RUIZ, Antonio; IRACHE , Juan Manuel; GONZALEZ-PENAS , Elena; SANMARTIN , Carmen; ESPUELAS , Socorro; ."3,5-Dimethyl-4-isoxazoyl selenocyanate as promising agent for the treatment of Leishmania infantum-infected mice". (ISSN: 0001-706X). Acta Tropica. 2020 , vol 215 , p. 105801 -  .

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• ETXEBESTE-MITXELTORENA , Mikel; PLANO , Daniel; ESPUELAS , Socorro; MORENO , Esther; AYDILLO , Carlos; JIMÉNEZ RUIZ, Antonio; GARCIA SORIANO , Juan Carlos; SANMARTIN , Carmen; ."New amides containing selenium as potent leishmanicidal agents targeting trypanothione reductase". (ISSN: 0066-4804). Antimicrobial Agents and Chemotherapy. 2020 , vol 65 , num 1 , p. e00524-20 -  .

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• LUCIO ORTEGA, Héctor Elessar de; TORO LONDOÑO, Miguel Ángel; CAMARASA RIUS, María José; VELÁZQUEZ DÍAZ, Sonsoles; GAGO BADENAS, Federico; JIMÉNEZ RUIZ, Antonio; ."Pseudoirreversible slow-binding inhibition of trypanothione reductase by a protein-protein interaction disruptor". (ISSN: 0007-1188). British Journal of Pharmacology. 2020 , vol 177 , num 22 , p. 5163 - 5176 .  .

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• GARNICA , P.; PLANO , D.; MORENO , E.; ESPUELAS , S.; PALOP , J.A.; JIMÉNEZ RUIZ, Antonio; SANMARTÍN , C.; ."Pre-clinical evidences of the antileishmanial effects of diselenides and selenocyanates". (ISSN: 0960-894X). Bioorganic and Medicinal Chemistry Letters. 2020 , vol 30 , p. 127371 -  .

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• LOSADA , Alejandro; BERLANGA , Juan José; MOLINA-GUIJARRO , José Manuel; JIMÉNEZ RUIZ, Antonio; GAGO BADENAS, Federico; AVILÉS MARÍN, Pablo Manuel; DE HARO , César; MARTÍNEZ LEAL, Juan Fernando; ."Generation of endoplasmic reticulum stress and inhibition of autophagy by plitidepsin induces proteotoxic apoptosis in cancer cells". (ISSN: 0006-2952). Biochemical Pharmacology. 2020 , vol 172 , p. 1137 -

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• REVUELTO , Alejandro; RUIZ-SANTAQUITERIA , Marta; LUCIO ORTEGA, Héctor Elessar de; GAMO , Ana; CARRILES , Alejandra; GUTIERREZ , Kilian Jesús; SÁNCHEZ MURCIA, Pedro Alejandro; HERMOSO , Juan A.; GAGO BADENAS, Federico; CAMARASA , María José; JIMÉNEZ RUIZ, Antonio; VELÁZQUEZ , Sonsoles; ."Pyrrolopyrimidine vs Imidazole-Phenyl-Thiazole Scaffolds in Nonpeptidic Dimerization Inhibitors of Leishmania infantum Trypanothione Reductase ". ACS Infectious Diseases. 2019 , vol 5 , num 6 , p. 873 - 891 .  .

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• BRAVO , Ana; LUCIO ORTEGA, Héctor Elessar de; SÁNCHEZ MURCIA, Pedro; JIMÉNEZ RUIZ, Antonio; PETRONE , Paula M.; GAGO BADENAS, Federico; CORTÉS CABRERA, Alvaro; ."Identification of NEK3 and MOK as novel targets for lithium". (ISSN: 1747-0277). Chemical Biology and Drug Design. 2019 .

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• AL-TAMINI , Abdul-Malek S.; ETXEBESTE-MITXELTORENA , Mikel; SANMARTÍN , Carmen; JIMÉNEZ RUIZ, Antonio; SYRJANEN , Leo; PARKKILA , Seppo; SELLERI , Silvia; CARTA , Fabrizio; ANGELI , Andrea; SUPURAN , Claudiu T.; ."Discovery of new organoselenium compounds as antileishmanial agents". (ISSN: 0045-2068). Bioorganic Chemistry. 2019 , vol 86 , p. 339 - 345 .

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• RUIZ SANTAQUITERIA, Marta; DE CASTRO , Sonia; TORO , Miguel; LUCIO ORTEGA, Héctor Elessar de; GUTIÉRREZ , Kilian Jesús; SÁNCHEZ MURCIA, Pedro; JIMÉNEZ , María Ángeles; GAGO BADENAS, Federico; JIMÉNEZ RUIZ, Antonio; CAMARASA , María José; VELÁZQUEZ , Sonsoles; ."Trypanothione reductase inhibition and anti-leishmanial activity of all-hydrocarbon stapled alfa-helical peptides with improved proteolytic stability". (ISSN: 0223-5234). European Journal of Medicinal Chemistry. 2018 , vol 149 , p. 238 - 247 .  .

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• LÓPEZ GUTIERREZ, Celia; LUCIO ORTEGA, Héctor Elessar de; GARCÍA SORIANO, Juan Carlos; JIMÉNEZ RUIZ, Antonio; ."Introducción del sistema CRISPR/Cas9 en Leishmania infantum". Dianas. 2017

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• OLIVA CORREIA, Cristina; SÁNCHEZ-MURCIA , Pedro A.; RICO VIDAL, Eva; BRAVO GARCÍA, Ana; MENÉNDEZ , Margarita; GAGO BADENAS, Federico; JIMÉNEZ RUIZ, Antonio; ."Structure-based domain assignment in Leishmania infantum EndoG: characterization of a pH-dependent regulatory switch and a C-terminal extension that largely dictates DNA substrate preferences.". (ISSN: 0305-1048). Nucleic Acids Research. 2017 , vol 45 , num 15 , p. 9030 - 9045 .

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• RUIZ-SANTAQUITERIA , Marta; SÁNCHEZ MURCIA, Pedro Alejandro; TORO , Miguel; DE LUCIO , Héctor; GUTIERREZ , Kilian Jesús; DE CASTRO , Sonia; CARNEIRO , Filipa; GAGO BADENAS, Federico; JIMÉNEZ RUIZ, Antonio; CAMARASA , María José; VELÁZQUEZ , Sonsoles; ."First example of peptides targeting the dimer interface of Leishmania infantum trypanothione reductase with potent in vitro antileishmanial activity". (ISSN: 0223-5234). European Journal of Medicinal Chemistry. 2017 , vol 135 , p. 49 - 59 .

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• MARIO GENES, Carlos; LUCIO ORTEGA, Héctor Elessar de; MANUEL GONZÁLEZ, Víctor; SÁNCHEZ MURCIA, Pedro Alejandro; RICO , Eva; GAGO BADENAS, Federico; FASEL , Nicholas; JIMÉNEZ RUIZ, Antonio; ."A functional BH3 domain in an aquaporin from Leishmania infantum". Cell Death Discovery. 2016 , vol 2 , num 16043 , p. 1 - 10 .  .

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• LUCIO ORTEGA, Héctor Elessar de; GENES ROBLES, Carlos Mario; SÁNCHEZ MURCIA, Pedro; GAGO BADENAS, Federico; JIMÉNEZ RUIZ, Antonio; ."Implicación del dominio BH3 de Li-BH3AQP en la muerte celular deL. infantum". Dianas. 2016

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• BAQUEDANO , Ylenia; ALCOLEA , V.; TORO , M.A.; GUTIÉRREZ , K.J.; NGUEWA , P.; FONT , M.; MORENO , E.; ESPUELAS , S.; JIMÉNEZ RUIZ, Antonio; PALOP , J. A.; PLANO , D.; SANMARTÍN , C.; ."Novel heteroaryl selenocyanates and diselenides as potent antileishmanial agents.". (ISSN: 0066-4804). Antimicrobial Agents and Chemotherapy. 2016 .

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• , Lopes RM; JIMÉNEZ RUIZ, Antonio; , Pereira J; , Esteves MA; , Gaspar MM; , Carvalheiro M; , Eleutério CV; , Gonçalves L; , Jiménez-Ruiz A; , Almeida AJ; , Cruz ME; ."Lipid-based nanoformulations of trifluralin analogs in the management of Leishmania infantum infections.". Nanomedicine (London, England). 2016 , vol 11 , p. 153 - 170

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• SÁNCHEZ MURCIA, Pedro; RUIZ SANTAQUITERIA, Marta; TORO , Miguel; LUCIO ORTEGA, Héctor Elessar de; JIMÉNEZ , María Ángeles; GAGO BADENAS, Federico; JIMÉNEZ RUIZ, Antonio; CAMARASA , María José; VELÁZQUEZ , Sonsoles; ."Comparison of hydrocarbon-and lactam-bridged cyclic peptides as dimerization inhibitors of Leishmania infantum trypanothione reductase". (ISSN: 2046-2069). RSC Advances. 2015 .

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• BAQUEDANO , Y.; ESPUELAS , E.; NGUEWA , P.; FONT , M.; GUTIERREZ , K.J.; JIMÉNEZ RUIZ, Antonio; PALOP , J. A.; SANMARTÍN , C.; ."Novel hybrid selenosulfonamides as potent antileishmanial agents". (ISSN: 0223-5234). European Journal of Medicinal Chemistry. 2014 , num 74 , p. 116 - 123 .

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• RICO , E.; GUTIERREZ , K.J.; ALZATE , J.F.; MORENO-MATEOS , D.; GENES , C.M.; CASANOVA , E.; GIGANTE , A.; PEREZ-PEREZ , M.J.; CAMARASA , M.J.; JIMÉNEZ RUIZ, Antonio; ."Leishmania infantum EndoG is an endo/exo-nuclease essential for parasite survival". (ISSN: 1932-6203). PLoS ONE. 2014

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• TORO LONDOÑO, Miguel Ángel; SÁNCHEZ-MURCIA , Pedro A.; MORENO MATEOS, David; RUIZ-SANTAQUITERIA , Marta; ALZATE RESTREPO, Juan Fernando; NEGRI MARTÍNEZ, Ana; CAMARASA RIUS, María José; GAGO BADENAS, Federico; VELÁZQUEZ , Sonsoles; JIMÉNEZ RUIZ, Antonio; SÁNCHEZ MURCIA, Pedro Alejandro; ."Probing the Dimerization Interface of Leishmania infantum Trypanothione Reductase with Site-Directed Mutagenesis and Short Peptides". (ISSN: 1439-4227). Chembiochem : a European journal of chemical biology. 2013 , num 4(10) , p. 1212 - 1217 .

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• CASANOVA MALPICA, Elena; MORENO MATEOS, David; GIGANTE MARTÍNEZ, Alba; RICO VIDAL, Eva; GENES ROBLES, Carlos Mario; OLIVA CORREIA, Cristina; CAMARASA RIUS, María José; GAGO BADENAS, Federico; JIMÉNEZ RUIZ, Antonio; PÉREZ PÉREZ, Mª Jesús; ."5'-Trityl-Substituted Thymidine Derivatives as a Novel Class of Antileishmanial Agents: Leishmania infantum EndoG as a Potential Target". (ISSN: 1860-7179). ChemMedChem. 2013 , num 8(7) , p. 1161 - 1174

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• BUEREN CALABUIG, Juan Antonio; CODERCH BOUÉ, Claire; RICO VIDAL, Eva; JIMÉNEZ RUIZ, Antonio; GAGO BADENAS, Federico; ."Mechanistic Insight into the Catalytic Activity of betabetaalfa-Metallonucleases from Computer Simulations: Vibrio vulnificus Periplasmic Nuclease as a Test Case". (ISSN: 1439-4227). Chembiochem : a European journal of chemical biology. 2011 , vol 12(17) , p. 2615 - 2622

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• PLANO , D; BAQUEDANO , Ylenia; MORENO-MATEOS , D.; FONT , M; PALOP , J. A.; JIMÉNEZ RUIZ, Antonio; SANMARTÍN , Carmen; ."Selenocyanates and diselenides: a new class of potent antileishmanial agents". (ISSN: 0223-5234). European Journal of Medicinal Chemistry. 2011 , vol 8 , num 46 , p. 3315 - 3323

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• MORENO , D.; PLANO , D.; BAQUEDANO , Y.; JIMÉNEZ RUIZ, Antonio; PALOP , J. A.; SANMARTÍN , C.; ."Antileishmanial activity of imidothiocarbamates and imidoselenocarbamates". (ISSN: 0932-0113). Parasitology Research. 2011 , vol 108 , num 1 , p. 233 - 239

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• TORO-LONDOÑO , MIguel; PATIÑO , Edwin Bairon; ROBLEDO , Sara María; JIMÉNEZ RUIZ, Antonio; ALZATE , J.F.; ."Leishmania (Viannia) panamensis expresses a nuclease with molecular and biochemical features similar to the Endonuclease G of higher eukaryotes". Colombia Médica. 2011 , num 42 , p. 154 - 165

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• SMIRLIS , P.; DUSZENKO , M.; JIMÉNEZ RUIZ, Antonio; SCOULICA , E.; BASTIEN , P.; FASEL , N.; SOTERIADOU , K.; ."Targeting essential pathways in trypanosomatids gives insights into protozoan mechanisms of cell death". (ISSN: 1756-3305). PARASITES & VECTORS. 2010 , vol 3 , p. 107 - 107

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• JIMÉNEZ RUIZ, Antonio; ALZATE , J.F.; MACLEOD , E.T.; LUDER , C.G.; FASEL , N.; HURD , H.; ."Apoptotic markers in protozoan parasites". (ISSN: 1756-3305). PARASITES & VECTORS. 2010 , vol 3 , num 1 , p. 104 - 104

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• NEGRI , A.; RODRIGUEZ-LARREA , D.; MARCO , E.; JIMÉNEZ RUIZ, Antonio; SANCHEZ-RUIZ , J.M.; GAGO BADENAS, Federico; ."Protein-protein interactions at an enzyme-substrate interface: characterization of transient reaction intermediates throughout a full catalytic cycle of Escherichia coli thioredoxin reductase". (ISSN: 0887-3585). Proteins: Structure, Function and Genetics. 2010 , vol 78 , num 1 , p. 36 - 51

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• RICO , E.; ALZATE , J.F.; ARIAS , A.A.; MORENO-MATEOS , D.; CLOS , J.; GAGO BADENAS, Federico; MORENO , I.; DOMINGUEZ , M.; JIMÉNEZ RUIZ, Antonio; ."Leishmania infantum expresses a mitochondrial nuclease homologous to EndoG that migrates to the nucleus in response to an apoptotic stimulus". (ISSN: 0166-6851). Molecular and Biochemical Parasitology. 2009 , vol 163 , num 1 , p. 28 - 38

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• ALZATE , J.F.; ARIAS , A.A.; MOLLINEDO , F.; RICO , E.; DE LA IGLESIA-VICENTE , J.; JIMÉNEZ RUIZ, Antonio; ."Edelfosine induces an apoptotic process in Leishmania infantum that is regulated by the ectopic expression of Bcl-XL and Hrk". (ISSN: 0066-4804). Antimicrobial Agents and Chemotherapy. 2008 , vol 52 , num 10 , p. 3779 - 3792

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• ALZATE , J.F.; ARIAS , A.A.; MORENO-MATEOS , D.; BARRIENTOS , A.A.; JIMÉNEZ RUIZ, Antonio; ."Mitochondrial superoxide mediates heat-induced apoptotic-like death in Leishmania infantum". (ISSN: 0166-6851). Molecular and Biochemical Parasitology. 2007 , vol 152 , num 2 , p. 192 - 202

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• ALZATE , J.F.; BARRIENTOS , A.A.; GONZÁLEZ , V.M.; JIMÉNEZ RUIZ, Antonio; ."Heat-induced programmed cell death in Leishmania infantum is reverted by Bcl-X(L) expression". (ISSN: 1360-8185). Apoptosis : an international journal on programmed cell death. 2006 , vol 11 , num 2 , p. 161 - 171

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• ALZATE , J.F.; RAMÍREZ-PINEDA , J.R.; GONZÁLEZ , V.M.; PATINO , E.; VELEZ , I.D.; JIMÉNEZ RUIZ, Antonio; ."Leishmania (Viannia) Panamensis: Cloning of the Histone H1 genes by Representational Difference Analysis". (ISSN: 0014-4894). Experimental Parasitology. 2006 , vol 112 , num 2 , p. 126 - 129

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• KEDZIERSKI , L.; MONTGOMERY , J.; BULLEN , D.; CURTIS , J.; GARDINER , E.; JIMÉNEZ RUIZ, Antonio; HANDMAN , E.; ."A Leucine-Rich Repeat Motif of Leishmania Parasite Surface Antigen 2 Binds to Macrophages through the Complement Receptor 3". (ISSN: 0022-1767). Journal of Immunology. 2004 , vol 172 , num 8 , p. 4902 - 4906

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• MORENO , M.; RINCÓN , E.; PINEIRO , D.; FERNANDEZ , G.; DOMINGO GALÁN, Alberto; JIMÉNEZ RUIZ, Antonio; SALINAS , M.; GONZÁLEZ , V.M.; ."Selection of aptamers against KMP-11 using colloidal gold during the SELEX process". (ISSN: 0006-291X). Biochemical and Biophysical Research Communications. 2003 , num 308 , p. 214 - 218

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• JIMÉNEZ RUIZ, Antonio; ALVÁREZ , N.; GONZÁLEZ , V.M.; ."Be careful with the primers when screening your clones by PCR". (ISSN: 0003-2697). Analytical Biochemistry. 2002 , num 308 , p. 189 - 191

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• PAREJA , J.C.; JIMÉNEZ RUIZ, Antonio; ."Mapping 3' termini of mRNA on DNA templates with Taq-Polymerase 3' end labelled probes". (ISSN: 0003-2697). Analytical Biochemistry. 2000 , num 280 , p. 185 - 186

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• BOCETA , C.; ALONSO , C.; JIMÉNEZ RUIZ, Antonio; ."Leucine rich repeats are the main epitopes in Leishmania infantum PSA during canine and human visceral leishmaniasis". (ISSN: 0141-9838). Parasite Immunology. 2000 , num 22(2) , p. 55 - 62

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• GONZÁLEZ , V.M.; FUERTES , M.A.; JIMÉNEZ RUIZ, Antonio; ALONSO , C.; PÉREZ , J.M.; ."The formation of DNA interstrand cross-links by a novel bis-[Pt2Cl4(diminazene aceturate)2]Cl4.4H2O complex inhibits the B to Z transition.". Molecular Pharmacology. 1999 , num 55 , p. 770 - 777

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• JIMÉNEZ RUIZ, Antonio; BOCETA , C.; BONAY , P.; REQUENA , J.M.; ALONSO , C.; ."Cloning, sequencing and expression of the PSA genes from Leishmania infantum". (ISSN: 00142956). European Journal of Biochemistry. 1998 , num 251 , p. 389 - 397

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• BERBERICH , Christof; MACHADO , Gloria; MORALES , Gracia; CARRILLO , Graciela; JIMÉNEZ RUIZ, Antonio; ALONSO , Carlos; ."The expression of the Leishmania infantum KMP-11 protein is developmentally regulated and stage specific". (ISSN: 0006-3002). Biochimica et Biophysica Acta. 1998 , num 1442 , p. 230 - 237

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• JIMÉNEZ RUIZ, Antonio; BOCETA , C.; ALONSO , C.; ."El antígeno de superficie PSA de Leishmania infantum. Un nuevo miembro de la familia de repeticiones ricas en Leucina.". (ISSN: 0004-2927). Ars Pharmaceutica. 1997 , num 38 , p. 295 - 303

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• JIMÉNEZ RUIZ, Antonio; REQUENA , J.M.; ALONSO , C.; ."Estructura y función del ADN en conformación Z. ". Investigación y Ciencia.. 1997 , p. 56 - 64

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• JIMÉNEZ RUIZ, Antonio; ZHANG , Q.; SHEN , C.-K.J.; ."In vivo binding of trimethyl-psoralen detects DNA structural alterations associated with transcribing regions in the human ß-globin cluster". (ISSN: 00219258). Journal of biological chemistry (Print). 1995 , num 270 , p. 28978 - 28981

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• REQUENA , J.M.; JIMÉNEZ RUIZ, Antonio; SOTO , M.; LÓPEZ , M.C.; ALONSO , C.; ."Characterization of a highly repeated interspersed DNA sequence of Trypanosoma cruzi: its potential use in diagnosis and strain classification". (ISSN: 0166-6851). Molecular and Biochemical Parasitology. 1992 , num 51 , p. 271 - 280

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• JIMÉNEZ RUIZ, Antonio; REQUENA , J.M.; SOTO , M.; ASSIEGO , R.; SANTAREN , J.F.; LÓPEZ , M.C.; PATARROYO , M.E.; ALONSO , C.; ."Regulation of hsp70 expression in Trypanosoma cruzi by temperature and growth phase". (ISSN: 0166-6851). Molecular and Biochemical Parasitology. 1992 , num 53 , p. 201 - 211

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• JIMÉNEZ RUIZ, Antonio; REQUENA , J.M.; LÓPEZ , M.C.; ALONSO , C.; ."A potential Z‑DNA‑forming sequence is located between two transcription units alternatively expressed during development of Drosophila hydei". (ISSN: 0027-8424). Proceedings of the National Academy of Sciences of the United States of America. 1991 , num 88 , p. 31 - 35

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• PÉREZ , J.M.; NAVARRO-RANNINGER , M.C.; REQUENA , J.M.; JIMÉNEZ RUIZ, Antonio; PARRONDO , E.; CRACIUNESCU , D.; LÓPEZ , M.C.; ALONSO , C.; ."DNA binding properties and antileukemic (L1210) activity of a Pt‑pentamidine complex". (ISSN: 0009-2797). Chemico-Biological Interactions. 1991 , num 77 , p. 341 - 345

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• SOTO , M.; REQUENA , J.M.; JIMÉNEZ RUIZ, Antonio; ALONSO , C.; ."The mRNA coding for the nucleosomal protein H2A of Leishmania is polyadenylated and has stem‑loops at the 3' end". Nucleic Acids Research. 1991 , num 19 , p. 4554 - 4554

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• MORALES , G.; REQUENA , J.M.; JIMÉNEZ RUIZ, Antonio; LÓPEZ , M.C.; UGARTE , M.; ALONSO , C.; ."Sequence and expression of the Drosophila phenylalanine hydroxylase mRNA". Gene. 1990 , num 93 , p. 213 - 219

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• LARAN , E.; REQUENA , J.M.; JIMÉNEZ RUIZ, Antonio; ALONSO , C.; ."Actual complexity of transcribing domains in Drosophila polytene chromosomes". Brotheria Genética . 1990 , num 9 , p. 155 - 170

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• LARAN , E.; REQUENA , J.M.; JIMÉNEZ RUIZ, Antonio; LÓPEZ , M.C.; ALONSO , C.; ."The heat shock protein hsp70 binds in vivo to subregions 2‑48BC and 3‑58D of the polytene chromosomes of Drosophila hydei". (ISSN: 0009-5915). Chromosoma. 1990 , num 99 , p. 315 - 320

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• REQUENA , J.M.; LÓPEZ , M.C.; JIMÉNEZ RUIZ, Antonio; MORALES , G.; ALONSO , C.; ."Complete nucleotide sequence of the hsp70 gene of T. cruzi". Nucleic Acids Research.. 1989 , num 17 , p. 797 - 797

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• JIMÉNEZ RUIZ, Antonio; REQUENA , J.M.; LANCILLOTTI , F.; MORALES , G.; LÓPEZ , M.C.; ALONSO , C.; ."Molecular cloning of a Drosophila potential Z-DNA forming sequence hybridizing in situ to a developmentally regulated subdivision of the polytene chromosomes". Nucleic Acids Research. 1989 , num 26 , p. 4579 - 4588

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• REQUENA , J.M.; LÓPEZ , M.C.; JIMÉNEZ RUIZ, Antonio; DE LA TORRE , J.C.; ALONSO , C.; ."A head-to-tail tandem organization of hsp 70 genes in Trypanosoma cruzi". Nucleic Acids Research. 1988 , num 16 , p. 1393 - 1406

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Electronic Articles

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Conferences

• JIMÉNEZ RUIZ, Antonio; REVUELTO , Alejanddro; CAMARASA , María José; GARCÍA , Juan Carlos; CARRILES , Alejandra; GUTIÉRREZ VIÑAS, Kilian Jesús; GUTIERREZ , Kilian; HERMOSO , Juan; CAMARASA RIUS, María José; VELÁZQUEZ , Sonsoles; ." Dimerization modulators of trypanothione reductase as innovative potent and selective Leishmanicidal agents. ". Congreso. Nacional. "19 Congreso de la SEQT. New Challenges in Drug Discovery". Vitoria-Gasteiz (2019 - 2019).

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• JIMÉNEZ RUIZ, Antonio; REVUELTO , Alejandro; LÓPEZ MARTÍN, I.; ZANDA , N.; LUCIO ORTEGA, Héctor Elessar de; GAGO BADENAS, Federico; CAMARASA , María José; VELÁZQUEZ , Sonsoles; ."Towards more potent peptide dimerization inhibitors of TryR of Leishmania infantum: exploring neighbouring hydrophobic binding-sites". Encuentro. Internacional. "16th IBERIAN PEPTIDE MEETING. 4TH CHEMBIO GROUP MEETING. Barcelona (España)". Barcelona (2018 - 2018).

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• JIMÉNEZ RUIZ, Antonio; ." A novel approach to inhibit trypanothione reductase in Trypanosomatids: Dimerization inhibitors" ". Congreso. Nacional. "41 Congreso de la Sociedad Española de Bioquímica y Biología Molecular". Santander (10/09/2018 - 13/09/2018).

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• BRAVO GARCÍA, Ana; JIMÉNEZ RUIZ, Antonio; ."Caracterización estructural y funcional de la enzima Endonucleasa G de Leishmania infantum, factores que regulan su actividad nucleasa.". Congreso. Nacional. "41 Congreso de la SEBBM - Santander 2018". Santander (10/09/2018 - 13/09/2018).

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• JIMÉNEZ RUIZ, Antonio; ."FIRST REPORTED POTENT IN VITRO ANTILEISHMANIALACTIVITY OF PEPTIDES THAT TARGET THE DIMER INTERFACE OF LEISHMANIA INFANTUM TRYPANOTHIONE". Congreso. Internacional. "VII EFMC International Symposium on Advances in Synthetic and Medicinal Chemistry Vienna, Austria | August 27-31, 2017". Viena "(Austria)". (27/08/2017 - 31/08/2017).

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• SANMARTÍN SALINA, Patricia; JIMÉNEZ RUIZ, Antonio; GONZÁLEZ GUIJARRO, Luis Alberto; ."Estudio de la función del IRS-4 en el eje Hipotalámico Hepático". Congreso. Nacional. "II Congreso de Señalización Celular, SECUAH 2017.". Alcalá de Henares (14/03/2017 - 16/03/2017).

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• JIMÉNEZ RUIZ, Antonio; ."Hydrocarbon-stapled peptides targeting the dimerization interface of Leishmania infantum trypanothione reductase". Congreso. Internacional. "MedChem 2013 anual one-day meeting on Medicinal Chemistry of KVCV and SRC. Constrained peptides and macrocycles-new opportunities for drug discovery". Beerse "(Bélgica)". (22/11/2013 - 22/11/2013).

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• JIMÉNEZ RUIZ, Antonio; ."Inhibitions of protein-protein interactions in trypanothione reductase (TryR) of Leishmania infantum: an innovative strategy". Nacional. "XVII national meeting SEQT". Madrid (02/10/2013 - 04/10/2013).

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• JIMÉNEZ RUIZ, Antonio; SÁNCHEZ MURCIA, Pedro Alejandro; ."Apoptotic-like function of Leishmania p32 protein in Saccharomyces cerevisiae". Congreso. Nacional. "XXXVI Congreso de la SEBBM ". Madrid (03/09/2013 - 06/09/2013).

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• JIMÉNEZ RUIZ, Antonio; SÁNCHEZ MURCIA, Pedro Alejandro; ."Structure-based domain assignment in Leishmania infantum EndoG and characterization of a pH-dependent regulatory switch". Nacional. Madrid (03/09/2013 - 06/09/2013).

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• JIMÉNEZ RUIZ, Antonio; ."Synthesis and biological evaluation of dimerization inhibitors of trypanothione reductase of Leishmania infantum". Nacional. "III SEQT summer school". Tres Cantos (25/07/2013 - 27/07/2013).

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• JIMÉNEZ RUIZ, Antonio; ."Involvement of the n-terminal domain in the expression of leishmania iInfantum tyrosine aminotransferase". Congreso. Internacional. "FEMS2013 - 5th Congress of European Microbiologists". Leipzig "(Alemania)". (21/07/2013 - 25/07/2013).

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• JIMÉNEZ RUIZ, Antonio; ."Disruptors of dimerization as inhibitors of Leishmania infantum trypanothione reductase". Congreso. Internacional. "Worldleish5". Porto Galinhas "(Brasil)". (13/05/2013 - 17/05/2013).

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• JIMÉNEZ RUIZ, Antonio; ."Identification of a Leishmania Bax inhibitor-1-related protein involved in cell death regulation". Congreso. Internacional. "Worldleish5". Porto Galinhas "(Brasil)". (13/05/2013 - 17/05/2013).

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• JIMÉNEZ RUIZ, Antonio; ."Leishmania infantum endonuclease G presents a self-inhibitor domain that regulates its activity". Congreso. Internacional. "Worldleish5". Porto Galinhas "(Brasil)". (13/05/2013 - 17/05/2013).

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• JIMÉNEZ RUIZ, Antonio; ."Novel assay to assess dimer disruption of L. infantum trypanothione reductase by peptides and small molecules.". Congreso. Internacional. "Worldleish5". (13/05/2013 - 17/05/2013).

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• BAQUEDANO , Ylenia; DOMÍNGUEZ , Enrique; PLANO , Daniel; FONT , Maria; PALOP , Juan Antonio; JIMÉNEZ RUIZ, Antonio; SANMARTÍN , Carmen; ."Design, synthesis and biological evaluation of new diselenide compounds as antileishmanial agents". Congreso. Internacional. "EFMC/ISMC CONGRESS". Berlin "(Alemania)". (02/09/2012 - 06/09/2012).

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• ROMANO , Beatriz; LAMBERTO , Iranzu; BAQUEDANO , Ylenia; IBÁÑEZ , Elena; CALVO , Alfonso; JIMÉNEZ RUIZ, Antonio; PALOP , Juan Antonio; SANMARTÍN , Carmen; ."Novel selenocarbamatoes as antiproliferative and antileishmanial agents". Congreso. Internacional. "EFMC/ISMC CONGRESS". Berlin "(Alemania)". (02/09/2012 - 06/09/2012).

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• BAQUEDANO , Ylenia; DÍAZ , Marta; LAMBERTO , Iranzu; DOMÍNGUEZ , Enrique; JIMÉNEZ RUIZ, Antonio; PALOP , Juan Antonio; SANMARTÍN , Carmen; ."Novel sulfonamides: a new class of potent antileishmanial agents". Congreso. Internacional. "EFMC/ISMC 2012 Congress". Berlin "(Alemania)". (02/09/2012 - 06/09/2012).

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• BUEREN CALABUIG, Juan Antonio; RICO VIDAL, Eva; OLIVA CORREIA, Cristina; JIMÉNEZ RUIZ, Antonio; GAGO BADENAS, Federico; ."Structural insights into Leishmania infantum endoG active site and analysis of the reaction mechanism ". Congreso. Internacional. "Second Iberic Meeting on Medicinal Chemistry: G rotein-Coupled Receptors and Enzymes in Drug Discovery ". Oporto "(Portugal)". (12/06/2011 - 15/06/2011).

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• JIMÉNEZ RUIZ, Antonio; ."International Training School". Workshop. Internacional. Alcalá de Henares (13/09/2010 - 18/09/2010).

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• JIMÉNEZ RUIZ, Antonio; ." Muerte celular programada en el parásito protozoo Leishmania infantum: características del proceso y moléculas implicadas". Congreso. Nacional. "XIV Congreso Colombiano de Parasitología y Medicina Tropical". Medellín "(Colombia)". (08/10/2009 - 11/10/2009).

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• MORENO-MATEOS , D.; ARIAS , A.A.; ALZATE , J.F.; JIMÉNEZ RUIZ, Antonio; ." Characaterizatin o the cell death process induced by ebselen in Leishmania infantum.". Congreso. Internacional. "WorldLeish 4". Lucknow "(India)". (03/02/2009 - 07/02/2009).

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• RICO , E.; ALZATE , J.F.; MORENO , D.; BUEREN , J.; GAGO BADENAS, Federico; JIMÉNEZ RUIZ, Antonio; ." Structural and functional analysis of Leishmania infantum EndoG". Congreso. Internacional. "WorldLeish 4". Lucknow "(India)". (03/02/2009 - 07/02/2009).

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• MORENO-MATEOS , D.; RICO , E.; ALZATE , J.F.; ARIAS , A.A.; CLOS , J.; GAGO BADENAS, Federico; JIMÉNEZ RUIZ, Antonio; ." Conservation of an endonuclease G like protein in Leishmania infantum.". Congreso. Internacional. "Molecular Parasitology Meeting XIX". Woodshole "(Estados Unidos)". (21/09/2008 - 25/09/2008).

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• RICO , E.; ALZATE , J.F.; MORENO , D.; ARIAS , A.A.; CLOS , J.; GAGO BADENAS, Federico; JIMÉNEZ RUIZ, Antonio; ." L. Infantum mitochondrion contains a nuclease homologous to EndoG that migrates to the nucleus in response to an apoptotic stimulus". Congreso. Internacional. Woodshole "(Estados Unidos)". (21/09/2008 - 25/09/2008).

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• ALZATE , J.F.; ALVAREZ BARRIENTOS , A.; GONZALEZ , V.M.; JIMÉNEZ RUIZ, Antonio; ."Analysis of the heat-induced cell death in Leishmania by flow-cytometry". Internacional. "Worldleish 3". "(Italia)". (10/04/2005 - ).

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• DEL ALAMO , M.; PÉREZ , A; CALVO , M.; JIMÉNEZ RUIZ, Antonio; GONZÁLEZ , V.M.; ALONSO , C.; DELGADO-IRIBARREN , A.; ."Evaluation of recombinant antigens and commercial assays for the diagnosis of Leishmaniasis". Conferencia. Internacional. "XXXVIII INTERSCIENCE CONFERENCE ON ANTIMICROBIAL AGENTS AND CHEMOTHHERAPY". San Diego "(Estados Unidos)". (09/1998 - ).

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• REQUENA , J.M.; JIMÉNEZ RUIZ, Antonio; LÓPEZ , M.C.; ALONSO , C.; ."Chromosomal Región 4?75C2 of D.hydei contains a cloned Z?forming sequence and it is in a transient B? to Z?DNA flux in vivo during development". Internacional. "Workshop on "Chromatine Structure and Gene Expression"". "(España)". (24/09/1990 - 26/09/1990).

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• REQUENA , J.M.; JIMÉNEZ RUIZ, Antonio; LARAN , E.; LÓPEZ , M.C.; ALONSO , C.; ."Hsp 70 binds in vivo to subregions 2?48BC and 3?58D of the Polytene chromosomes of Drosophila hydei.". Internacional. "Workshop on Heatshock". Ravello "(Italia)". (17/09/1990 - 20/09/1990).

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• PÉREZ , J.M.; REQUENA , J.M.; JIMÉNEZ RUIZ, Antonio; LÓPEZ , M.C.; ALONSO , C.; ."Análisis Bioquímico y Estructural del análogo de Platino: cis?dicloro (pentamidina) Platino III". Nacional. "XVI Congreso Nacional de Bioquímica". "(España)". (10/1989 - 31/10/1989).

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• REQUENA , J.M.; JIMÉNEZ RUIZ, Antonio; MORALES , G.; ALONSO , C.; ."Clonaje de un gen inducible por ecdisona en la región 4?75C de D.hydei.". Nacional. "XVI Congreso Nacional de Bioquímica". "(España)". (10/1989 - 31/10/1989).

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• REQUENA , J.M.; JIMÉNEZ RUIZ, Antonio; MORALES , G.; LÓPEZ , M.C.; ALONSO , C.; ."Secuencias formadoras de Z?DNA en Drosophila hydei". Europeo. "III Congreso Luso Español de Bioquímica". "(España)". (09/1988 - 30/09/1988).

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Theses

• OLIVA CORREIA, Cristina; "Caracterización funcional y estructural de la endonucleasa G de Leishmania infantum. Exploración de su potencial como diana para el desarrollo de agentes terapéuticos con actividad leishmanicida.". Director: JIMÉNEZ RUIZ, Antonio, GAGO BADENAS, Federico, . UNIVERSIDAD DE ALCALA. Reading date: 28/07/2020. Sobresaliente cum laude.

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• LUCIO ORTEGA, Héctor Elessar de; "Inhibición de la tripanotión reductasa de Leishmania infantum mediada por peptidomiméticos de la hélice Alpha2 de la interfaz de dimerización". Director: JIMÉNEZ RUIZ, Antonio, GAGO BADENAS, Federico, . UNIVERSIDAD DE ALCALA. Reading date: 02/11/2018. Sobresaliente cum laude.

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• TORO LONDOÑO, Miguel Ángel; "Diseño y evaluación de inhbidores peptídicos dirigidos a la interfaz de dimerización de la tripanotión reductasa de Leishmania infantum". Director: JIMÉNEZ RUIZ, Antonio, GAGO BADENAS, Federico, . UNIVERSIDAD DE ALCALA. Reading date: 30/06/2017. Sobresaliente cum laude.

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• GENES ROBLES, Carlos Mario; "Muerte celular similar a apoptosis en Leishmania spp: una aproximaciókn a su regulación". Director: JIMÉNEZ RUIZ, Antonio, . UNIVERSIDAD DE ALCALA. Reading date: 19/07/2013. sobresaliente cum laude.

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• RICO VIDAL, Eva; "Estudio de la nucleasa EndoG en el protozoo Leishmania infantum: caracterización e implicaciones en la supervivencia y muerte del parásito". Director: JIMÉNEZ RUIZ, Antonio, GAGO BADENAS, Federico, . European mention . UNIVERSIDAD DE ALCALA. Reading date: 15/11/2010. Sobresaliente cum laude.

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• MORENO MATEOS, David; "Estrategias celulares y moleculares en el cribado de nuevos agentes anti-Leishmania". Director: JIMÉNEZ RUIZ, Antonio, GAGO BADENAS, Federico, . UNIVERSIDAD DE ALCALA. Reading date: 24/07/2010. Sobresaliente cum laude.

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